王權(quán)威, 董振, 王桂武, 楊福合, 劉慧, 李春義
中國(guó)農(nóng)業(yè)科學(xué)院特產(chǎn)研究所 特種動(dòng)物分子生物學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室,長(zhǎng)春 130112
【摘要】鹿茸是迄今為止發(fā)現(xiàn)的唯一能夠周期性再生的哺乳動(dòng)物器官,它的生長(zhǎng)速度極快卻沒有發(fā)生癌變。而蛋白質(zhì)是生命活動(dòng)的體現(xiàn)者,是生命活動(dòng)的功能執(zhí)行者,鹿茸相關(guān)蛋白的研究是揭開鹿茸再生秘密的重要途徑。綜述了鹿茸再生相關(guān)蛋白的篩選、血管生成相關(guān)蛋白、軟骨形成相關(guān)蛋白、神經(jīng)再生相關(guān)蛋白以及其他與鹿茸再生相關(guān)蛋白的研究進(jìn)展,旨在為從蛋白質(zhì)水平上揭示鹿茸再生過(guò)程提供基礎(chǔ)資料。
【關(guān)鍵詞】鹿茸再生相關(guān)蛋白; 血管生成; 軟骨形成; 神經(jīng)再生
Research Progress on Proteins Related to Deer Antler Regeneration
Wang Quanwei, Dong Zhen, Wang Guiwu, Yang Fuhe, Liu Hui, Li Chunyi
State Key Lab for Molecular Biology of Special Animals/Institute of Special Animal and Plant Sciences,Chinese Academy of Agricultural Science,Changchun 130112
【Abstract】Deer antler is an only known mammalian organ that can periodically regenerate, and grow very rapidly without going cancerous. Proteins are the carrier and the function executor of life activities, the research of proteins related to deer antler is an important measure to unlock the secrets of antler’s regeneration. The proteins involved in angiogenesis, cartilage formation, nerve regeneration and other functions during antler regeneration are reviewed which aims at providing basic data for revealing antler regeneration process at the protein level.
【Keywords】proteins related to deer antler regeneration; angiogenesis; cartilage formation; nerve regeneration
收稿日期：2014-11-03
基金項(xiàng)目：國(guó)家科技支撐計(jì)劃（2011BAI03B02）,國(guó)家“973”計(jì)劃（2012CB722907）,吉林省自然科學(xué)基金項(xiàng)目（201115129）,吉林省科技支撐重點(diǎn)項(xiàng)目（20120965）
